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DOE Low Dose Radiation Research
Investigators' Workshop VI
Abstracts
Principal Investigator |
Abstract Title |
| Anderson, Carl |
Whole Genome Analysis of Functional Protein Binding Sites and DNA Methylation: Application to p53 and Low Dose Ionizing Radiation. |
| Averbeck, Dietrich |
Cellular Responses at Low Doses of Ionizing Radiation |
| Azzam, Edouard |
Adaptive Responses to Low Dose/Low Dose-Rate γ-Rays in Normal Human Fibroblasts: The Role of Oxidative Metabolism |
| Bailey, Susan |
The Role of Telomere Dysfunction in Driving Genomic Instability |
| Balajee, Adayabalam |
Low Dose Radiation Induced DNA Damage Signaling and Repair Responses in Human 3-Dimensional Skin Model System |
| Barcellos-Hoff, Mary Helen |
Biological Response to Radiation Mediated through the Microenvironment and Multicellular Interactions |
| Barcellos-Hoff, Mary Helen |
Imaging Bioinformatics for Mapping Multidimensional Responses |
| Bedford, Joel |
γH2AX Foci after Low Dose-Rate Irradiation Reveal a Defect in DNA DSB Processing in Cells from Unaffected Parents of Retinoblastoma Patients, ATM Heterozygotes, and Other Apparently Normal Humans |
| Blakely, Ellie |
Low-LET Bystander Effects In Cells In Vitro Are Significantly Less Than Published For High-LET Radiation |
| Sykes, P.J. and Blyth, B.J. |
Low Dose Radiation Exposure: Exploring Bystander Effects In Vivo. |
| Boothman, David |
Low dose ionizing radiation (IR) signaling regulation in vivo versus in vitro of the IGF-1/IGF-1R pathway leading to the synthesis of pro-survival secretory clusterin expression: Roles for p53/Hdm2 |
| Bouffler, Simon |
Radiation Leukaemogenesis at Low Doses |
| Brenner, David |
The Bystander Effect in Normal Human 3-D Tissue: Experiments, Models, and Implications |
| Brooks, Antone |
Optimizing the Scientific Regulatory and Societal Impact of the DOE Low Dose Radiation Research Program |
| Campisi, Judith |
Molecular mediators of radio-adaptation in human cells |
| Chen, David J. |
Live Cell Imaging and in situ analysis of cellular responses to DNA doublestrand breaks in mammalian cells. |
| Chen, David J. |
The Role of DNA double-strand break repair in cellular response to low dose radiation exposure. |
| Chen, Xian |
Comparative Proteomic Analysis of the HSF Cells Exposed to IR at Different Doses: Identification of Unique Proteins Sensitive to Low-dose IR |
| Chen, Xian |
Identification of Rad52 complexes reveals a functional link between DNA repair and cytokinesis |
| Chuang, Eric |
Abnormal Gene Expression of Four Genes in Cells from Family Members of Hereditary-type Retinoblastoma Patients Relative to Normal Individuals |
| Coleman, Matthew |
Co-Regulation Among Genes and Pathways that are Responsive to Low-Dose Ionizing Radiation |
| Cooper, Priscilla |
Connections Between the TCR Proteins XPG and CSB, Repair of Oxidative DNA Base Damage, and the Radio-Adaptive Response |
| Cornforth, Michael |
Chromosome Rearrangements in the Clonal Descendants of hTERT-Immortalized Human Cells Exposed to Gamma Rays |
| Cucinotta, Francis |
Stochastic Models of Space Radiation DNA Damage Responses and Cancer Risks |
| Spitz, D.R., Dayal, Disha |
Hydrogen peroxide significantly contributes to radiation-induced genomic instability |
| Brenner, D., Dubrova, Yuri |
Is Increased Low-Dose Somatic Radiosensitivity Associated with Increased Trans-Generational Germline Mutation Radiosensitivity? |
| Dynan, William |
Low Dose Radiation Injury and Radioprotection in the Vertebrate Embryo |
| Folkman, Judah |
Biphasic Dose-efficacy in Antiangiogenic Therapy |
| Fornace, Albert |
Radiation-induced Responses Involved in Intercellular Signaling and in vivo Effects |
| Goldberg, Zelanna |
Human In Vivo Dose Response to Controlled, Low-Dose Low LET Ionizing Radiation Exposure |
| Grdina, David and Jeff Murley |
Prevention of Low Dose Radiation-Induced Genomic Instability with Clinically Relevant Non-Protein Thiols and Vitamin E. |
| Green, Lora |
Comparative Assessment of Radiation-Induced Gene Expression in Two-Dimensional Versus Three-Dimensional Thyroid Cultures |
| Gridley, Daila |
Low Dose Photon Radiation-Induced Changes in T Helper Lymphocytes |
| Gridley, Daila |
Protracted Low Dose Photon and Simulated Solar Flare Proton Effects on Cytokine/ Chemokine Expression After Whole-Body Irradiation |
| Sachs, R.K., Hahnfeldt, Philip |
Radiation Carcinogenesis Risk as Influenced by Intercellular Interaction |
| Hall, Eric |
Genetic Susceptibility |
| Holman, Hoi-Ying |
High-Resolution Infrared Spectromicroscopy for Molecular Characterization of Low-LET Bystander Effects |
| Jirtle, Randy |
Radiation and the Fetal Epigenome |
| Kadhim, Munira |
Mechanisms Underlying Cellular Responses to Low Doses/Low LET Ionizing Radiation in Primary Haemopoietic Cells. |
| Bissell, Mina, J., Kenny, Paraic |
3D Tissue Models for the Study of the Effects of Low-Dose Irradiation |
| Kronenberg, Amy |
Optimizing dual detection of epithelial cell markers and EGFP for use in bystander studies |
| Voy, Brynn, Langston, Michael |
Scalable Computational Methods for Analysis of the Low Dose Radiation Transcriptome |
| Li, Chuan-Yuan |
The Roles of Superoxide Dismutage (SOD) in Low Dose Radiation Induced Adaptive Response |
| Li, Jian Jian |
NF-κB Mediated Signaling Network in Low Dose X-Ray InducedAdaptive Protection of Mouse and Human Skin Epithelial Cells |
| Liu, Annie T.Y., Spitz, Douglas |
Antioxidant Enzyme Overexpression Protects Cells with a Mutation in Succinate Dehydrogenase Subunit C (SDHC) from Low Dose Irradiation Radiation |
| Mao, Jiang-Hua, Balmain, A. |
Genomic signatures for radiation-induced mouse lymphoma |
| Marchetti, Francesco, Wyrobek, Andrew |
Pathway Analyses of Ionizing Radiation-Responsive Proteins in Mammals |
| Miller, John |
Application of Ab-Initio Quantum and Classical Molecular Dynamics Simulations to Study Clustered DNA Damage |
| Morgan, William |
Genetic Factors Affecting Susceptibility to Low-Dose Radiation |
| Morgan, William, Marianne Sowa |
Using a Low-LET Electron Microbeam to Investigate Non-Targeted Effects of Low Dose Radiation |
| Nagasawa, Hatsumi |
The alpha-particle induced bystander effect for sister chromatid exchanges in Fancg-deficient CHO cells |
| Natarajan, Mohan |
SHP-2 tyrosine phosphate-dependent focal adhesion kinase mediated cell migration of primary endothelial cells upon low LET radiation exposure. |
| Natarajan, Mohan |
Tumor Cell-mediated bystander response on the angiogenic potentials of endothelium. |
| Olsen, Anders, Campisi, J. |
Molecular Mechanisms of Low Dose Radiation Mediated Hormesis in C. elegans |
| O'Neill, Peter |
Co-localisation of γ-H2AX and 53BP1 to sites of DNA double strand breaks following low- and high-LET irradiation of mammalian cells |
| Opresko, Lee and Marianne Sowa |
Morphological changes in a 3D Mammary Model Following Exposure to Low Dose, Low-LET Radiation |
| Prise, Kevin |
Targeted Radiation Studies in Tissue Explants |
| Redpath, Leslie |
The Effect of Dose-Rate on Radiation-Induced Neoplastic Transformation In Vitro by Low Doses of Low LET Radiation |
| Rithidech, Kanokporn Noy |
No evidence for in vivo induction of genomic instability in bone marrowcells collected from mice exposed to low-dose |
| Rodgers, Brenda |
Assessment of Time-course Exposures in BALB/c Mice Following 137Cs Gamma Irradiation |
| Sabatier, Laura |
European Integrated Project RISC-RAD Radiosensitivity of Individuals and Susceptibility to Cancer induced by Ionizing Radiations |
| Sacksteder, Colette |
Molecular Mechanism Underlying Cellular Adaptive Response to Low Dose Radiation |
| Sakai, Kazuo |
Suppression of Tumorigenesis by Adaptive Response in Mice |
| Salomaa, Sisko and Oleg Belyakov |
Non-targeted Effects of Ionising Radiation (NOTE) – A New European Integrated Project, 2006-2010 |
| Schwartz, Jeff |
Characteristics of Radiation-Induced Basal Cell Skin Cancer in Pediatric and Adult Hematopoietic Cell Transplant Recipients |
| Schwartz, Jeff |
Chronic Low Dose Radiation Effects on Radiation Sensitivity and Chromosome Instability Induction in TK6 Cells |
| Scott, Bobby |
Low-Dose/Dose-Rate Low-LET Radiation Protects Us from Cancer |
| Spitz, Douglas R. |
Mitochondrial-Derived Oxidants and Cellular Responses to Low Dose/Low LET Ionizing Radiation |
| Springer, David |
Identification and Characterization of Factors Involved in Delayed Effects of Radiation |
| Sutherland, Betsy |
Clustered DNA Damage Spectrum in Primary Human Hematopoietic Stem Cells from Smokers is Similar to the Radiation-Induced Damage Spectrum |
| Sykes, Pamela |
Adaptive and reverse adaptive responses for chromosomal inversions in pKZ1 mouse prostate: hints on mechanism |
| Thompson, Larry |
Assessment of Individual Variation in DNA Double-Strand Break Repair Capacity in Human Diploid Fibroblasts |
| Vo-Dinh, Tuan |
Nanoprobes for Imaging Single Cells under Low-Dose Radiation |
| Voy, Brynn |
Genetic Variation in the Transcriptomic Response to Low Dose Radiation In Vivo |
| Wang, Daojing |
Proteomic and Biochemical Studies of Human Mesenchymal Stem Cells in Response to Low Dose Ionizing Radiation |
| Warters, Raymond |
Assessment of the p53 response of keratinocytes in culture and in intact human skin |
| Weber, Thomas |
Annexin A2 Regulates A Low Dose-Specific Stress Response To Radiation. |
| Wyrobek, Andrew |
Molecular Mechanisms and Cellular Consequences of Low-dose Exposure to Ionizing Radiation |
| Yannone, Steve |
Persistent DNA Damage foci, Cellular Senescence and Low Dose Radiation |
| Yuan, Zhi-Min |
A Heightened Radiosensitivity of Stromal Fibroblasts in 3D Matrix |
| Zimbrick, John |
Transgenerational Effects of Chronic Low-Dose Irradiation in a Medaka Fish Model System |
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