About the Program :)
















 

Carl W. Anderson
Brookhaven National Laboratories
E-mail: cwa@bnl.gov
Website: http://www.biology.bnl.gov/cellbio/anderson.html


About the Project:

Whole Genome Analysis of Functional Protein Binding Sites and DNA Methylation: Potential Application to p53 and Low Dose Ionizing Radiation

Newly Funded Projects:

Analysis of Human Proteins Induced in Response to Ionizing Radiation

Technical Abstracts

Publications:

Appella, E. and Anderson, C.W. (2007) New prospects for proteomics: Electron-capture (ECD) and electron-transfer dissociation (ETD) fragmentation techniques and combined fractional diagonal chromatography (COFRADIC). FEBS J. 274(24):6255

Chao, C., Wu, Z., Mazur, S.J., Borges, H., Rossi, M., Lin, T., Wang, J.Y.J., Anderson, C. W., Apella, E., and Xu, Y. (2006) Acetylation of mouse p53 at lysine 317 negatively regulates p53 apopaotic activities after DNA damage. Molecular and Cellular Biology 26: 6859-6869.

Dunn, J.J., McCorkle, S.R., Everett, L., and Anderson, C.W.,. (2006) Paired-end genomic signature tags: A method for the functional analysis of genomes and epigenomes. Genetic Engineering: Principles and Methods 28:159-173.

Shreeram, S., Demidov, O.N., Hee, W.K., Yamaguchi, H., Onishi, N., Kek, C., Timofeev, O.N., Dungeon, C., Fornace, Jr. A.J., Anderson, C.W., Minami, Y., Appella, E., and Bulavin, D.V. (2006) Wip1 phosphatase modulates ATM-dependent signaling pathways. Molecular Cell 23:757-764.

Sheeram, S., Hee, W.-K., Demidov, O.N., Kek, C., Yamaguchi, H., Fornace, A.J., Anderson, C.W., Appella, E., and Bulavin, D.V. (2006) Regulation of ATM/p53-dependent suppression of myc-induced lymphomas by Wip 1 phosphatase. Journal of Experimental Medicine 203:2793-2799.

Yamaguchi, H., Durell, S.R., Feng, H., Bai, Y., Anderson, C.W., and Appella, E. (2006) Development of a substrate-based cyclic phosphopoptide inhibitor of protein phosphatase 2C δ , Wip 1. Biochemistry 45:13192-13202.

Yamaguchi, H., Minopoli, G., Demidov, O.N., Chatterjee, D.K., Anderson, C.W., Durell, S.R., and Appella, E. (2005) Substrate specificity for the human protein phosphatase 2C, Wip1 Biochemistry 44:4285-5294.

 



                   
                   
                   
 

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