About the Program :)
















 

Robert D. Stewart
Purdue University
E-mail: trebor@purdue.edu
Website: http://rh.healthsciences.purdue.edu/faculty/rds.html


Currently Funded Projects:

Modeling: Towards Constructing and Testing a Virtual Tissue

Kinetic Modeling of Damage Repair, Genome Instability, and Neoplastic Transformation



Technical Abstracts:

Publications:

Stewart, R ., D., Ratnayake, R.K., and Jennings, K. (2006) Microdosimetric model for the induction of cell killing through medium-borne signals. Radiation Research 165(4):460-469.

Schöllnberger, H., Stewart, R.D., and Mitchel, R.E.J. (2005) Low-LET induced radioprotective mechanisms within a stochastic two-stage cancer model. Dose-Response 3(4):508-518.

Ratnayake, R.K., Semenenko, V.A., and Stewart, R.D. (2005) Retrospective analysis of DSB rejoining data collected using warm-lysis PFGE protocols. International J. of Radiation Biology 81(6):421-428.

Semenenko, V.A. and Stewart, R.D. (2005) Monte Carlo simulation of base and nucleotide excision repair of clustered DNA damage sites: II. Comparisons of model predictions to measured data. Radiation Research 164(2):194-201.

Semenenko, V.A., Stewart, R.D., Ackerman, E.J. (2005) Monte Carlo simulation of base and nucleotide excision repair of clustered DNA damage sites: I. Model properties and predicted trends. Radiation Research 164(2):180-193.

Schöllnberger, H., Stewart, R.D., Mitchel, R.E.J., and Hofmann, W. (2004) An examination of radiation hormesis mechanisms using a multi-stage carcinogenesis model. Nonlinearity in Biology, Toxicology and Medicine 2:317-352.

Semenenko, V.A. and Stewart, R.D. (2004) A fast Monte Carlo algorithm to simulate the spectrum of DNA damages formed by ionizing radiation. Radiation Research 161(4):451–457.

Guerrero, M., Stewart, R.D., Wang J., and Li, X.A. (2002) Equivalence of the linear-quadratic and two-lesion kinetic models. Phys. Med. Biol. 47(17):3197-3209.

Presentations:

"Biologically-Based Modeling of Human Health Effects of Low Dose Ionizing Radiation," In: Application of DNA damage and pathway-specific repair models to radiation mutagenesis. Fred Hutchinson Cancer Research Center, Seattle, WA., July 2005.

 
 



                   
                   
                   
 

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